Prelims GS Paper IScience & TechnologyHigh-yield

General Science — Biology (Cell, Genetics, Disease, Nutrition, Human Body)

सामान्य विज्ञान — जीव विज्ञान (कोशिका, आनुवंशिकी, रोग, पोषण)

General Science — Biology (Cell, Genetics, Disease, Nutrition, Human Body) is part of the UPSC Prelims GS Paper I syllabus, under Science & Technology. It appeared in Prelims GS Paper I question papers in 6 of the 10 years from 2016 to 2025 (2016, 2018, 2020, 2022, 2024, 2025). It is marked high-yield: a topic worth revising more than once.

What should you study in General Science?

  • Cell biology — prokaryote vs eukaryote, cell organelles
  • Genetics — DNA, RNA, gene expression, CRISPR-Cas9
  • Human diseases — communicable (TB, HIV, malaria) vs non-communicable
  • Nutrition — macronutrients, micronutrients, deficiency diseases

How often is General Science asked in UPSC Prelims?

Asked in 6 of 10 years, including 3 of the last 5. Highlighted years below are the ones it appeared in.

  1. 2016: asked
  2. 2017: not asked
  3. 2018: asked
  4. 2019: not asked
  5. 2020: asked
  6. 2021: not asked
  7. 2022: asked
  8. 2023: not asked
  9. 2024: asked
  10. 2025: asked

About the Prelims GS Paper I paper

General Studies Paper I is the Prelims paper that decides the cut-off: 100 multiple-choice questions for 200 marks, with negative marking for wrong answers. See all 88 Prelims GS Paper I topics.

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